How is this scientific knowledge useful? Three ways:1. A calorie is not a calorie, considering that a calorie of protein is five steps away from body fat—convert into amino acids, convert to glucose, meet up with insulin, transform to fatty acids, and hook up with glycerol-3-phospate—while a calorie of fa
t is only two steps away—convert into fatty acids and hook up with glycerol-3-phospate. 2. It is impossible to store glucose as body fat without enough insulin. inSANE starches and sweets trigger a flood of insulin in our body. That’s one of the reasons we should shy away from them. 3. No body fat gets stored without glycerol-3-phospate. Guess where we get the most glycerol-3-phospate? InSANE starches and sweets. Put this all together and it gets clearer why eating more—but smarter—works while eating less does not. When people eat less, they are still overeating since their metabolism slows down. Additionally, they have plenty of insulin and glycerol-3-phospate thanks to the inSANE low-quality starches and sweets they continue eating. Overeating plus insulin and glycerol-3-phospate means new body fat. 
Source: The Smarter Science of Slim

How is this scientific knowledge useful? Three ways:
1. A calorie is not a calorie, considering that a calorie of protein is five steps away from body fat—convert into amino acids, convert to glucose, meet up with insulin, transform to fatty acids, and hook up with glycerol-3-phospate—while a calorie of fa

t is only two steps away—convert into fatty acids and hook up with glycerol-3-phospate. 

2. It is impossible to store glucose as body fat without enough insulin. inSANE starches and sweets trigger a flood of insulin in our body. That’s one of the reasons we should shy away from them. 

3. No body fat gets stored without glycerol-3-phospate. Guess where we get the most glycerol-3-phospate? InSANE starches and sweets. 

Put this all together and it gets clearer why eating more—but smarter—works while eating less does not. When people eat less, they are still overeating since their metabolism slows down. Additionally, they have plenty of insulin and glycerol-3-phospate thanks to the inSANE low-quality starches and sweets they continue eating. Overeating plus insulin and glycerol-3-phospate means new body fat. 

Source: The Smarter Science of Slim